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Dr. Otto Octavius (Alfred Molina) is a brilliant scientist and Peter Parker (Tobey Maguire) finds him to be a kindred spirit after meeting with him to get some background for a school report. He may be the mentor for which Peter has been searching as he has time for both romance and science much like Peter would like to have with Mary Jane Parker (Kirsten Dunst). But Peter’s view of him is sadly torn asunder when he discovers that this kind and gentle soul has morphed into Doc Ock following the laboratory accident which has fused mechanical arms to his body and killed his beloved.
- Director: Sam Raimi
- Writer: Stan Lee; Steve Ditko; Alfred Gough; Miles Millar; Michael Chabon; Alvin Sargent
- Cast:
- Tobey Maguire - Spider-Man/Peter Parker
- Kirsten Dunst - Mary Jane Watson
- James Franco - Harry Osborn
- Alfred Molina - Doc Ock/Dr. Otto Octavius
- Rosemary Harris - May Parker
- J.K. Simmons - J. Jonah Jameson
- Donna Murphy - Rosalie Octavius
- Daniel Gillies - John Jameson
- Dylan Baker - Dr. Curt Connors
- Bill Nunn - Joseph ‘Robbie’ Robertson
- Vanessa Ferlito - Louise
- Aasif Mandvi - Mr. Aziz
- Willem Dafoe - Green Goblin/Norman Osborn
- Cliff Robertson - Ben Parker
- Ted Raimi - Hoffman
- Elizabeth Banks - Miss Brant
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